Devices and integration matter because the more your tech can work together, the more freedom you get in your day-to-day life. From tubed systems to tubeless pods and closed-loop AI-assisted pumps, here’s a snapshot of key diabetes technology available now — including t:slim, Mobi, Omnipod 5, Medtronic MiniMed 780G, Beta Bionics iLet, twiist, and more.
What Is Automated Insulin Delivery (AID)?
Automated Insulin Delivery systems combine a CGM, an insulin pump, and an algorithm to automatically fine-tune insulin delivery throughout the day and night. They’re sometimes called “hybrid closed-loop” systems because they still require manual input for meals, but they reduce the mental load of background insulin adjustments.
Tandem t:slim X2 & Tandem Mobi
Type: Tubed Insulin Pump (t:slim X2); Compact option (Mobi)
Insulin Capacity: 300 unit reservoir (t:slim X2); 200 unit reservoir (Mobi)
CGM Integrations: Dexcom G6, Dexcom G7, and Abbott FreeStyle Libre 3 Plus sensors in Control-IQ+ mode
Snapshot: The t:slim X2 is a mainstream AID system with a color touchscreen, rechargeable battery (often lasting up to ~7 days depending on use), and predictive Control-IQ+ technology that helps prevent highs and lows. Mobi is a smaller, more streamlined variant aimed at users who want a more compact pump with similar integration. Mobi users can view pump/CGM data and deliver boluses from an app on compatible phones. Not only can users can wear Mobi in an adhesive patch with 5" tubing, Tandem has announced that they are working on a patch version of Mobi.
Insulet Omnipod 5
Type: Tubeless Patch Pump (Pod)
Insulin Capacity: Pods typically last ~3 days per pod (72 hours) before replacement and hold up to 200 units of insulin
CGM Integrations: Dexcom G6 and Dexcom G7 sensors
Snapshot: Omnipod 5 brings hybrid closed-loop automation without tubes, meaning a pump pod sits directly on your body and delivers insulin continuously. SmartAdjust™ technology updates insulin delivery every ~5 minutes based on CGM data. Its small, waterproof pods and optional smartphone (iPhone/Android) control make it popular for people who prefer a less obtrusive setup.
Medtronic MiniMed 780G
Type: Tubed Insulin Pump with Advanced AID
Insulin Capacity: Up to 300 units
CGM Integrations: Medtronic’s Guardian 4 Sensor (with future expansion to Abbott FreeStyle Libre tech)
Shapshot: MiniMed 780G uses Medtronic’s SmartGuard™ algorithm, including advanced features like Meal Detection and frequent (every ~5 minutes) adjustments based on CGM readings. It also supports an extended infusion set worn up to ~7 days, meaning fewer site changes.
Beta Bionics iLet Bionic Pancreas System
Type: Closed-Loop AID System
Insulin Capacity: Up to 200 units of insulin
CGM Integrations: Dexcom G6, Dexcom G7, Abbott FreeStyle Libre 3 Plus
Snapshot: iLet is designed to be even more “hands-off” than traditional AID systems — it adapts insulin delivery based on body weight and CGM data without requiring preset basal rates or complex settings. Some versions emphasize minimal manual correction and learning insulin patterns automatically, making it a promising choice for people who want more automation and less micromanagement.
twiist AID System (by Sequel Med Tech)
Type: AID Pump
Insulin Capacity: 300 units
CGM Integrations: Designed for use with popular CGMs (Dexcom, others; see approvals per region and clinician guidance)
Snapshot: twiist is an emerging hybrid closed-loop pump system powered by interoperable algorithms that aim to offer personalized automated insulin delivery using real-time CGM data. As with other advanced systems, compatibility and specific features may vary by region and approval status.
How Integrations Work (CGMs + Pumps)
The strength of these systems lies in integration — the pump needs real-time glucose info to adjust insulin delivery automatically. Many of the pumps above pair with the Dexcom G6 or G7 sensors, which transmit readings every ~5 minutes. Some systems also work with other sensors like the FreeStyle Libre 3 Plus, depending on region and prescription.
| System | Type | Reservoir/Pod Wear | Typical Insulin Capacity | CGM Integration | Notable Features |
|---|---|---|---|---|---|
| Tandem t:slim X2 | Tubed AID Pump | Tubed infusion set changed every ~2–3 days | ~300 units (pump) | Dexcom G6, Dexcom G7, FreeStyle Libre 3 Plus | Control-IQ+ algorithm, predictive adjustments |
| Tandem Mobi | Compact Tubed AID Pump | Tubed infusion set ~2–3 days | ~200 units | Dexcom G6, Dexcom G7, FreeStyle Libre 3 Plus | Smaller form factor, same Control-IQ+ tech |
| Insulet Omnipod 5 | Tubeless Pod Pump (AID) | Pod replaced ~72 hours | ~200 units (per pod) | Dexcom G6, Dexcom G7 | Pod directly on body, SmartAdjust™ AID |
| Medtronic MiniMed 780G | Tubed AID Pump | Tubed infusion set up to ~7 days | ~300 units | Medtronic Guardian 4; Abbott Instinct; Simplera Sync | SmartGuard™ + Meal Detection |
| Beta Bionics iLet | AID Pump / Bionic Pancreas | Tubed infusion set ~2–3 days | ~200 units | Dexcom G6, Dexcom G7, FreeStyle Libre 3 Plus | Algorithm learns patterns automatically |
| twiist (Sequel Med Tech) | Tubed AID Pump (new) | Tubed infusion sets ~2–3 days | ~300 units | Works with compatible FreeStyle Libre 3 Plus; will soon work with the Eversence | FDA-cleared AID with micro-dosing |
