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DIABETES MANAGEMENT
Your go-to hub for tips, tricks, and real talk on living boldly with diabetes
The Biggest Diabetes Clinical Trials to Watch Right Now
Type 1 diabetes research has never been busier. Every year, researchers launch new clinical trials exploring better ways to treat, prevent, and one day fundamentally change the course of type 1 diabetes. Some are focused on slowing the autoimmune attack that causes the disease. Others are working to replace the insulin-producing cells that have been lost. And some are tackling one of the biggest remaining challenges: helping those new cells survive for the long term. Here are some of the clinical trials generating the most excitement in the type 1 diabetes community today. Preserving Beta Cells After Diagnosis For decades, diabetes treatment has largely focused on replacing the insulin the body can no longer produce. A growing area of research asks a different question: what if we could preserve the insulin-producing beta cells that remain after diagnosis? Researchers know that many people continue producing small amounts of insulin for months (or even years) after being diagnosed with type 1 diabetes. Several clinical trials are investigating whether immune therapies can protect those remaining cells and extend their function. Baricitinib Originally approved to treat rheumatoid arthritis, baricitinib is now being studied as a way to slow the immune attack responsible for type 1 diabetes. Early research suggests it may help preserve insulin production in people who have been recently diagnosed, though larger studies are still needed to understand its long-term role in diabetes care. Anti-Thymocyte Globulin (ATG) Another promising approach involves anti-thymocyte globulin (ATG), an immune-modulating therapy that's been used in transplantation medicine for years. Researchers are studying whether carefully adjusting the immune response shortly after diagnosis can help preserve beta cell function and extend what's commonly known as the honeymoon phase. Why it matters: Even preserving a small amount of natural insulin production can make blood sugar management easier and may reduce the risk of severe hypoglycemia and long-term complications. Researchers aren't trying to stop diabetes overnight – they're trying to help the body hold onto what it still has. Delaying Type 1 Diabetes Before It Starts One of the biggest shifts in diabetes research is happening before someone is ever diagnosed. Scientists now understand that type 1 diabetes develops gradually, often years before symptoms appear. During that time, the immune system is already attacking insulin-producing cells, even though blood sugars may still be normal. That discovery has opened the door to prevention studies. TrialNet TrialNet is one of the world's largest type 1 diabetes research networks. Through screening programs for relatives of people with type 1 diabetes, researchers can identify individuals who are at increased risk long before symptoms develop. Those discoveries have led to numerous prevention studies aimed at slowing or delaying disease progression. Tzield (Teplizumab) One of the biggest milestones to come out of this work is Tzield (teplizumab), the first FDA-approved therapy shown to delay the onset of Stage 3 type 1 diabetes in certain high-risk individuals. While Tzield is now an approved treatment, researchers continue to study how similar immune therapies—or combinations of therapies—might delay diagnosis even longer or benefit additional groups of people. Why it matters: These studies are changing the conversation from treating type 1 diabetes after diagnosis to potentially delaying it before symptoms even begin. Replacing the Cells Lost to Type 1 Diabetes Perhaps the most closely watched area of research today is cell replacement therapy. Instead of improving insulin delivery, these studies are attempting to restore the body's ability to produce insulin by replacing the beta cells destroyed by the immune system. Vertex Pharmaceuticals Vertex has become one of the biggest names in this space with zimislecel (formerly VX-880), an investigational therapy created from stem cell-derived islet cells. The treatment is designed to replace insulin-producing cells in people with type 1 diabetes, allowing the body to once again make its own insulin. Early clinical results have been encouraging, with several participants achieving insulin independence following treatment while receiving immunosuppressive therapy. Larger studies are now underway to evaluate long-term safety and effectiveness. Vertex also explored a second program, VX-264, which aimed to protect transplanted cells inside an implanted device to avoid lifelong immunosuppression. Although that program has since been discontinued, the broader goal of protecting transplanted cells without suppressing the immune system remains an active area of research. Why it matters: These studies aren't focused on making insulin therapy better. They're exploring whether the body can regain the ability to produce insulin at all. Making Cell Therapy Safer Replacing beta cells is only part of the challenge. The immune system still recognizes those new cells as something to attack, which is why many transplant recipients currently require lifelong immunosuppressive medications. Several clinical trials are focused on improving that process. Eledon Pharmaceuticals Eledon is studying tegoprubart, an investigational anti-CD40L antibody designed to protect transplanted islet cells while potentially avoiding some of the drawbacks associated with traditional immunosuppressive medications. Recent investigator-led studies at the University of Chicago have shown encouraging results, with participants achieving insulin independence following islet transplantation while maintaining stable graft function. Sernova Sernova is taking a complementary approach with its Cell Pouch platform, a small implanted device designed to house insulin-producing cells in an environment where they can survive and function. The company is evaluating the Cell Pouch alongside newer immunosuppressive strategies, including a collaboration with Eledon to study tegoprubart as part of its ongoing clinical program. Why it matters: Replacing insulin-producing cells is only half the battle. Finding safer, less toxic ways to protect those cells could make future cell therapies a realistic option for many more people living with type 1 diabetes. Final Thoughts Clinical trials rarely produce overnight breakthroughs. Progress usually happens one carefully designed study at a time. Today's investigational therapies won't change diabetes care tomorrow, but they are helping answer important questions that could shape the future of treatment for years to come. Type 1 diabetes research isn't moving in just one direction. It's advancing on multiple fronts, with scientists around the world working toward the same goal: improving life with type 1 diabetes through smarter, safer, and more effective therapies. Clinical trials evolve quickly as new participants enroll, studies conclude, and additional data become available. This article reflects the current research landscape at the time of publication and highlights several of the most closely watched clinical trials in type 1 diabetes.
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The Best Diabetes Camps and Retreats for Kids, Teens, and Adults
For kids, camp can be the first time they realize they aren't the only person wearing a pump or CGM. For teens and young adults, these experiences can provide community during a stage of life that often comes with increasing independence and new challenges. And for adults, retreats and conferences offer something many people have never experienced before: spending time with others who understand the daily realities of diabetes without needing an explanation. In fact, with the median age of diagnoses now at 24, many adults never had the opportunity to connect with other people with diabetes in childhood. These programs create opportunities to build confidence, share experiences, learn from others, and form friendships that often last long after the event ends. Whether you're looking for a traditional summer camp, an outdoor adventure retreat, a family conference, or a community meetup, there are more options available today than ever before. American Diabetes Association Camps For many families, ADA camps are the introduction to the world of diabetes camping. These programs are offered in locations across the country and combine traditional camp activities with diabetes education and medical support. Campers have the opportunity to build independence, learn new skills, and spend time with peers who understand life with diabetes. For many children, it's the first time they realize they're not alone in their experience. Diabetes Youth Foundation (DYF) DYF has been creating diabetes camp experiences for decades and offers a variety of programs for children, teens, and families. Their camps focus on confidence-building, leadership development, and community, helping participants navigate diabetes while still enjoying all the classic camp experiences. Many families remain connected to DYF long after their first camp session ends. Camp Sweeney Located in Texas, Camp Sweeney is one of the most well-known diabetes camps in the country. For generations, it has provided children with diabetes the opportunity to experience camp in an environment designed specifically for their needs. Campers leave with new skills, greater confidence, and often lifelong friendships. Camp Kudzu For families in the Southeast, Camp Kudzu has become a beloved part of the diabetes community. Based in Georgia, the organization offers camps, family programs, teen leadership opportunities, and year-round events designed specifically for children and adolescents living with type 1 diabetes. What makes Camp Kudzu especially impactful is its emphasis on community beyond the summer months. Through leadership programs, family events, and ongoing support opportunities, many participants remain connected long after camp ends. For countless campers, it's not just a week away from home—it's the place where they meet lifelong friends who understand exactly what life with diabetes is like. The Diabetes Link The Diabetes Link focuses heavily on supporting college students and young adults living with type 1 diabetes. Through in-person meetups, campus chapters, and community programming, the organization helps bridge the gap between pediatric and adult care while fostering meaningful peer connections during a pivotal stage of life. Connected in Motion Connected in Motion has redefined what diabetes community can look like for adults. Their Slipstream Retreats bring adults with type 1 diabetes together for outdoor adventures ranging from hiking and paddling to skiing and camping. The focus is less on formal education and more on building confidence, community, and the reminder that diabetes does not have to limit adventure. For many attendees, it's the first time they've ever been surrounded by dozens of people who understand exactly what it's like to live with type 1 diabetes. You're Just My Type You're Just My Type approaches diabetes community through the lens of connection and mental well-being. The nonprofit hosts events and experiences that bring together people living with type 1 diabetes and their families in supportive, welcoming environments. Their work focuses on creating spaces where people can build relationships, share experiences, and feel understood. While the activities may look different from a traditional camp, the outcome is often the same: meaningful connection with people who simply get it. Riding On Insulin Riding On Insulin combines diabetes community with outdoor adventure. Known for its ski and snowboard programs, the organization helps participants challenge themselves while learning from mentors and peers who also live with diabetes. Their programs reinforce an important message: diabetes should never be a barrier to pursuing the activities you love. Friends for Life Hosted by Children with Diabetes, Friends for Life is one of the largest diabetes gatherings in the world. Part conference, part community event, and part family reunion, Friends for Life brings together children, adults, caregivers, healthcare professionals, and advocates for a week of education and connection. Many attendees describe it as one of the few places where nearly everyone around them understands life with diabetes. iChallenge Diabetes iChallenge Diabetes (ICD) focuses on helping people with diabetes pursue adventure, travel, and outdoor experiences with confidence. Through retreats, adventure programs, and community events, participants have opportunities to challenge themselves while building connections with others who understand the realities of life with diabetes. From hiking and outdoor recreation to leadership development and peer support, ICD's programs reinforce the idea that diabetes doesn't have to hold anyone back from pursuing ambitious goals. ConnecT1D Adult Retreat ConnecT1D's Adult Retreat was created specifically for adults living with type 1 diabetes who are looking for connection, education, and community. The retreat combines expert-led sessions with opportunities to connect with others who understand the day-to-day realities of managing diabetes. For many attendees, it's a chance to step away from everyday responsibilities and spend time with people who simply "get it." The result is often a mix of practical learning, meaningful friendships, and renewed confidence. Diabetes Sangha Not every diabetes retreat centers around adventure or education. Diabetes Sangha takes a different approach by focusing on mindfulness, emotional well-being, and community. Through retreats and virtual programs, participants explore practices like meditation, self-compassion, and stress management alongside others living with diabetes. For people looking to strengthen not only their diabetes management but also their relationship with themselves, Diabetes Sangha offers a unique perspective within the diabetes community. Not Sure Where to Start? DECA Can Help With so many camps, retreats, and community experiences available, figuring out where to begin can feel overwhelming. The Diabetes Education & Camping Association (DECA) serves as a valuable resource for families and individuals looking to explore diabetes camps across North America. Through DECA, you can discover programs in your area, learn about different camp experiences, and find opportunities that fit your age, interests, and goals. If you're not sure which camp or retreat is right for you, DECA is often one of the best places to start. Final Thoughts Technology has transformed diabetes management, but it hasn't replaced the need for community. Whether it's a week at summer camp, a college retreat, an outdoor adventure, or a conference filled with people who understand your experience, these programs offer something that's difficult to find elsewhere: a sense of belonging. Diabetes camps and retreats aren't just for kids anymore. They're opportunities for connection, confidence, and community at every stage of life.
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Diabetes Tech Fails: The Backup Plans Everyone Should Have
Diabetes technology has come a long way. Modern pumps, CGMs, and automated insulin delivery systems can make daily life easier, provide more insight than ever before, and help reduce some of the mental load that comes with managing diabetes. But even the best technology has bad days. A sensor can fail halfway through a vacation. A pod can leak right before an important meeting. A pump battery can die at the worst possible time. Most people who wear diabetes technology long enough eventually discover an unwritten rule: It's not a matter of if something will go wrong. It's a matter of when. The good news is that a little preparation can turn most tech failures from a major crisis into a minor inconvenience. The Best Backup Plan Is the One You Already Have Nobody wants to spend time preparing for a problem that may never happen. But diabetes technology is a lot like travel insurance. You hope you never need it, but you're grateful it's there when you do. The most stressful device failures tend to happen when there's no backup plan in place. A failed sensor at home is annoying. A failed sensor during a weekend camping trip is a different story. Thinking through a few common scenarios ahead of time can make all the difference. Keep More Supplies Than You Think You'll Need One of the most common pieces of diabetes advice is also one of the most valuable: pack extra. Then pack a little more. This applies whether you're heading across the country or simply spending the day away from home. Extra supplies might include: A backup sensor An extra infusion set or pod Charging cables Alcohol wipes Adhesive products Low snacks Backup insulin, including long acting if you're on a pump Syringes Technology tends to fail at inconvenient times. Having supplies readily available can save hours of frustration. Sensor Failures Happen Even the most reliable CGM occasionally has a bad sensor. Sometimes it's inaccurate. Sometimes it loses signal. Sometimes it simply stops working before its expected wear time. While replacement programs from manufacturers are often helpful, they don't solve the immediate problem. Keeping one extra sensor on hand can prevent a small issue from turning into several days without CGM data. It's also worth remembering that your meter still has a role to play. Many people tuck theirs away once they start using a CGM, only to rediscover it during a sensor failure. Travel Requires a Different Level of Preparation Diabetes technology and travel have a complicated relationship. Time zone changes, long flights, unexpected delays, lost luggage, dead batteries, and unfamiliar environments all introduce new variables. Experienced travelers often keep diabetes supplies in multiple locations: Primary carry-on bag Personal item Travel companion's bag, if applicable This way, one misplaced backpack doesn't take all of your supplies with it. It's also smart to keep manufacturer support numbers accessible while traveling, especially if you're relying heavily on technology during your trip. Keep in mind, most airlines will allow you to bring an extra carry-on bag at no cost for medical supplies. If you're a pump user, be sure to check with your manufacturer about loaner pumps as a backup for longer travel. Screenshots Can Save the Day This may be one of the least talked-about diabetes hacks. Keeping screenshots of: Prescriptions Insurance approvals Pump settings Device serial numbers Pharmacy information can be surprisingly helpful. When a device fails unexpectedly, having key information readily available can make replacement and troubleshooting processes much smoother. When a Pump Fails: Don't Panic Pump failures can feel especially intimidating because they affect insulin delivery directly. Unlike a failed sensor, a failed pump often requires immediate action. The first step is simple: don't panic. Most pump manufacturers offer replacement programs and can often overnight a new device. The bigger challenge is making sure you have a safe plan for insulin in the meantime. This is one reason many endocrinologists recommend keeping a current prescription for long-acting insulin, even if you haven't used it in years. If your pump fails completely, transitioning back to injections can help bridge the gap until a replacement arrives. Remember, this also requires having a prescription for pen needle tips and syringes. Every person's insulin needs are different, so it's important to have a plan from your healthcare team for exactly how much long-acting insulin to take if this situation arises. Keeping those instructions written down somewhere (or in your notes app) can save a lot of stress when you need them most. Switching Back to Your Pump Requires a Plan, Too One detail that catches many people off guard is what happens when the replacement pump finally arrives. Long-acting insulin doesn't disappear the moment you reconnect your pump. Depending on the insulin used, it may continue working for anywhere from 18 to 42 hours after injection. Starting your normal basal program too soon can result in overlapping insulin delivery and increase the risk of hypoglycemia. Many healthcare providers recommend waiting until the long-acting insulin has largely worn off before resuming normal basal rates. Others may suggest using a temporary basal setting or delaying pump initiation depending on the specific insulin involved. This is another reason it's helpful to have a written "pump failure plan" from your diabetes care team before you actually need one. The best time to figure out what you'll do during a pump failure is before a pump failure happens. Final Thoughts Modern diabetes technology is incredible, but it's still technology. Sensors fail. Pods leak. Batteries die. Apps crash. Adhesives lift. Having a plan for those moments doesn't mean expecting the worst. It means giving yourself a little extra peace of mind when life inevitably throws a curveball. The best diabetes setup isn't the one that never experiences problems. It's the one that's ready when they happen.
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